Which antibiotics cause QT prolongation?
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Charlotte Taylor
Studied at the University of Lagos, Lives in Lagos, Nigeria.
As a medical professional with expertise in pharmacology, I can provide you with information on antibiotics that are known to potentially cause QT prolongation, which is a heart rhythm abnormality that can be life-threatening.
Several antibiotics have been associated with QT prolongation, including but not limited to:
1. Macrolide antibiotics: Erythromycin, clarithromycin, and azithromycin.
2. Fluoroquinolones: Levofloxacin, moxifloxacin, and ciprofloxacin.
3. Tetracyclines: Gatifloxacin (which has been withdrawn in some countries due to safety concerns).
4. Antifungal medications: Voriconazole and posaconazole.
5. Others: Telithromycin (also withdrawn from the market due to safety concerns), linezolid, and isepamicin.
It's important to note that not all patients will experience QT prolongation while taking these medications, and the risk can be influenced by factors such as dosage, duration of treatment, underlying health conditions, and the presence of other medications that can also affect the QT interval.
Works at the International Fund for Agricultural Development, Lives in Rome, Italy.
Antimicrobials. Macrolides (erythromycin, clarithromycin), fluoroquinolones, antifungals, and antimalarials have been implicated in predisposing to TdP as a result of QT prolongation.
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Isabella Stewart
QuesHub.com delivers expert answers and knowledge to you.
Antimicrobials. Macrolides (erythromycin, clarithromycin), fluoroquinolones, antifungals, and antimalarials have been implicated in predisposing to TdP as a result of QT prolongation.
