What is the digitalis effect?

As a medical expert with a focus on pharmacology and cardiology, I can provide you with an accurate description of the digitalis effect. The digitalis effect is a term used to describe the characteristic changes that can be observed on an electrocardiogram (ECG) in individuals who have been treated with digitalis, a medication derived from the foxglove plant. Digitalis, specifically its active component digoxin, is used to treat certain heart conditions, such as atrial fibrillation and heart failure. The ECG changes associated with the digitalis effect include: 1. ST-segment depression: This is often downsloping and can have a distinctive appearance, sometimes referred to as a "Salvador Dali sagging" look, which is a reference to the surreal and drooping nature of the ST segments. 2. T-wave abnormalities: These can manifest as flattened, inverted, or biphasic T waves. The T waves may appear to be more rounded or scooped out, which is indicative of the digitalis effect. It's important to note that while these ECG changes are indicative of digitalis therapy, they are not exclusive to it and can be seen in other conditions as well. Overdosage of digitalis can lead to serious cardiac effects, including arrhythmias, and thus, the ECG is a crucial tool in monitoring patients on this medication.

Digoxin effect refers to the presence on the ECG of: Downsloping ST depression with a characteristic ��Salvador Dali sagging�� appearance. Flattened, inverted, or biphasic T waves.