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Is a strong Nucleophile a strong base?

Harper Turner | 2023-06-08 10:00:11 | page views：1926
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Ethan Davis

Works at the International Labour Organization, Lives in Geneva, Switzerland.
Some charged nucleophiles are actually poor bases. ... So if you see a nucleophile like NaCl, NaBr, KCN, and so on, it will favor SN2 over E2. In contrast, the bulky base below (tert-butoxide ion) is a strong base but a poor nucleophile due to its great steric hindrance, so an E2 reaction is much more likely than SN2.Nov 30, 2012
2023-06-16 10:00:11
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Amelia Lewis

QuesHub.com delivers expert answers and knowledge to you.
Some charged nucleophiles are actually poor bases. ... So if you see a nucleophile like NaCl, NaBr, KCN, and so on, it will favor SN2 over E2. In contrast, the bulky base below (tert-butoxide ion) is a strong base but a poor nucleophile due to its great steric hindrance, so an E2 reaction is much more likely than SN2.Nov 30, 2012
Deciding SN1/SN2/E1/E2 (2) �C The Nucleophile/Base �� Master ...
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